Read e-book online Melt Extrusion: Materials, Technology and Drug Product PDF

By Michael A. Repka,Nigel Langley,James DiNunzio

ISBN-10: 1461484316

ISBN-13: 9781461484318

This quantity offers readers with the elemental ideas and basics of extrusion know-how and a close description of the sensible purposes of quite a few extrusion tactics, together with quite a few pharma grade extruders. moreover, the downstream creation of flicks, pellets and pills, for instance, for oral and different supply routes, are provided and mentioned using soften extrusion. This ebook is the 1st of its style that discusses broadly the well-developed technology of extrusion know-how as utilized to pharmaceutical drug product improvement and production. by way of masking a variety of correct themes, the textual content brings jointly all technical info essential to boost and marketplace pharmaceutical dosage kinds that meet present caliber and regulatory necessities. As extrusion expertise is still sophisticated additional, utilization of extruder platforms and the array of functions will proceed to extend, however the middle applied sciences will stay the same.

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Download PDF by Lois E. Krahn,Michael H. Silber,Timothy I. Morgenthaler: Atlas of Sleep Medicine

By Lois E. Krahn,Michael H. Silber,Timothy I. Morgenthaler

ISBN-10: 041545008X

ISBN-13: 9780415450089

Written through skilled participants from the popular Mayo medical institution, the Atlas of Sleep and Sleep Medicine covers the background, humanities, and comparative organic points of sleep. This hugely illustrated source comprises images, reproductions, snap shots, segments of sleep stories, and scientific algorithms to assist the clinician within the right analysis and administration of sleep disorders.

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Next Generation Antibody Drug Conjugates (ADCs) and by Ulf Grawunder,Stefan Barth PDF

By Ulf Grawunder,Stefan Barth

ISBN-10: 3319468758

ISBN-13: 9783319468754

This publication describes the latest advancements in antibody drug conjugates and immunotoxins, paving their solution to medical program. classes discovered from the present state-of-the-art are used to additional increase our realizing in their mechanisms of motion and rancid aim activities.

The publication introduces scientists to all the necessities that needs to be accurately addressed, together with id of the proper aim, particular characteristics of goal binding antibodies, right choice of the poisonous payload, internalization prompted through binding, and subsequent iteration conjugation and linker applied sciences. those knowledge-based, innovative new drug rules will shape the cornerstone of the longer term commonplace of care and should bring about significant advances in software, in addition to better caliber of existence and sufferer survival charges. This ebook should be of curiosity to biotech businesses and researchers operating within the fields of immunology, pharmacology, and oncology.

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Download e-book for kindle: Reproductive Toxicology, Third Edition (Target Organ by Robert W. Kapp,Rochelle W. Tyl

By Robert W. Kapp,Rochelle W. Tyl

ISBN-10: 0781702259

ISBN-13: 9780781702256

Thoroughly reading the preferred and increasing box of reproductive toxicology, this newly revised and extended 3rd variation presents the most recent, state-of-the-art clinical advancements during this consistently evolving self-discipline. Reproductive Toxicology’s participants are skilled regulatory business enterprise and scientific study association representatives who presently make the most of the hot suggestions mentioned within the textual content and proceed to revolutionize reproductive toxicology research.

This ground-breaking source includes:

  • New and critical serious mechanistic subject matters reminiscent of epigenetics and omics

  • The first major compilation of epigenetic mechanisms

  • An in-depth research of the function of genomics, proteomics, and metabolomicsin human reproduction

  • New directions with appreciate to the newest examine functions within the field

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Download e-book for iPad: Drug-Induced Liver Disease by Laurie D.DeLeve,Neil Kaplowitz,Laurie D. DeLeve

By Laurie D.DeLeve,Neil Kaplowitz,Laurie D. DeLeve

ISBN-10: 0824708113

ISBN-13: 9780824708115

Featuring greater than 4100 references, Drug-Induced Liver sickness could be a useful reference for gastroenterologists, hepatologists, relations physicians, internists, pathologists, pharmacists, pharmacologists, and scientific toxicologists, and graduate and clinical tuition scholars in those disciplines.

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Download e-book for kindle: The Vitamins by Gerald Combs Jr.

By Gerald Combs Jr.

ISBN-10: 012183493X

ISBN-13: 9780121834937

The 3rd version of this bestselling textual content will back give you the most modern assurance of the biochemistry and body structure of supplementations and vitamin-like components. commonly revised and multiplied at the foundation of contemporary learn findings with enlarged assurance of future health results of vitamin-like components, it really is superb for college kids and a massive reference for someone drawn to food, nutrients technology, animal technological know-how or endocrinology. It includes a cohesive and well-organized presentation of every of the supplements, in addition to the heritage in their discoveries and present information regarding their roles in foodstuff and health.

*Includes nearly 30% new material
*Substantial updates were made to chapters on supplementations A, C, E, okay, folate, and the quasi-vitamins
*Provides checklists of structures tormented by diet deficiencies and nutrition assets of vitamins
*Key recommendations, studying ambitions, vocabulary,case stories, examine questions and extra interpreting lists are incorporated making this best for students
* completely up to date with vital fresh learn effects, together with citations to key studies, many additional tables and several other new figures.
*Addition of healthiness and meals exam Survey (HANES III) data
*Updated nutritional Reference Values

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Bonnie S. Bachenheimer's Manual for Pharmacy Technicians PDF

By Bonnie S. Bachenheimer

ISBN-10: 1585282073

ISBN-13: 9781585282074

The relied on education source for pharmacy technicians in any respect levels.

The function of pharmacy technicians is speedily increasing, and insist for well-trained technicians hasn't ever been greater! Technicians are assuming extra tasks and are taking up higher management roles. caliber education fabric is more and more vital for brand spanking new technicians coming into the sphere, and present technicians seeking to advance.

Look no extra than the hot 4th variation of the best-selling handbook for Pharmacy Technicians to grasp the sensible talents and achieve the foundational wisdom all technicians have to be successful.

NEW chapters conceal the most recent essentials:

* uniqueness Pharmacy Practice
* verbal exchange and Teamwork
* Billing and Reimbursement
* sturdy and Nondurable scientific gear, units, and Supplies

NEW positive factors include:

* Rx for achievement packing containers percentage the right way to support techs excel at the job
* expertise issues spotlight the most recent in automation & technical areas
* safeguard First beneficial properties offer serious suggestion for boosting security & decreasing errors
* Bolded keywords outlined in chapter-level glossaries
* Streamlined contents divide e-book into four easy components: creation to pharmacy perform, origin wisdom and talents, perform fundamentals, and enterprise applications
* extended self-assessment questions and calculations content

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Download e-book for iPad: Freeze-Drying/Lyophilization of Pharmaceutical and by Louis Rey

By Louis Rey

ISBN-10: 1439825750

ISBN-13: 9781439825754

Freeze-drying, or lyophilization, is a good proven expertise utilized in the upkeep of various pharmaceutical and organic items. This powerful dehydration technique comprises the elimination of water from frozen fabrics through the direct sublimation of ice. in recent times, this technique has met with many adjustments, as have the rules that impression lyophilization practices. This quantity addresses those alterations with revised chapters on rising advancements in lyophilization know-how, study, and techniques. supplying either a systematic and business standpoint, this entire textual content is a priceless source for all those that use freeze-drying know-how.

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Download e-book for iPad: Long Acting Injections and Implants (Advances in Delivery by Jeremy C. Wright,Diane J. Burgess

By Jeremy C. Wright,Diane J. Burgess

ISBN-10: 146140553X

ISBN-13: 9781461405535

ISBN-10: 1489989137

ISBN-13: 9781489989130

Long performing injections and implants enhance remedy, increase sufferer compliance, increase dosing comfort, and are the main applicable formula selection for medicines that endure wide first go metabolism or that convey terrible oral bioavailability.  An exciting number of applied sciences were built to supply lengthy appearing injections and implants.  Many issues have to cross into the layout of those structures so as to translate an idea from the lab bench to real treatment for a sufferer.  This e-book surveys and summarizes the field. 

Topics lined in Long appearing Injections and Implants contain the ancient improvement of the sphere, medications, ailments and scientific functions for lengthy performing injections and implants, anatomy and body structure for those structures, particular injectable applied sciences (including lipophilic recommendations, aqueous suspensions, microspheres, liposomes, in situ forming depots and self-assembling lipid formulations), particular implantable applied sciences (including osmotic implants, drug eluting stents and microfabricated systems), peptide, protein and vaccine supply, sterilization, drug liberate checking out and regulatory points of lengthy appearing injections and implants.

This quantity presents crucial info for knowledgeable improvement execs yet was once additionally written to be invaluable for scientists simply starting paintings within the box and for others who want an figuring out of lengthy appearing injections and implants.  This e-book may also be excellent as a graduate textbook.

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Pharmacokinetics and Pharmacodynamics of Abused Drugs - download pdf or read online

By Steven Karch MD FFFLM,Steven B.,Steven B. Karch MD FFFLM

ISBN-10: 1420054589

ISBN-13: 9781420054583

Extracted from the Drug Abuse guide, 2nd version, to provide you simply the data you would like at a reasonable price.

Pharmacokinetics and Pharmacodynamics of Abused Drugs is a concise and concentrated quantity dedicated to the metabolism and measurable results of substances at the human physique. starting with simple options and versions designed to supply a basic knowing of the subject material, the e-book info the specifics of absorption, distribution, and removing pathways and charges of more often than not abused medications. It analyzes the results of drug use on human functionality together with reaction time, reminiscence and remember, logical and cognitive tactics, in addition to physiological adjustments. filled with info and comparative reviews, this convenient quantity considers the consequences of advertised and prescription medicines in addition to illicit medications together with opioids, hashish, cocaine, methamphetamine, MDMA, ketamine, nicotine, and LSD. Containing 29 figures and tables and wide references, this can be a must-have source for the impact of drug use and abuse on human body structure and performance.

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